RECURRENT RESPIRATORY PAPILLOMATOSIS

Abstract

Objective of this article was to review the current knowledge regarding the etiology, clinical presentation and therapeutic procedure available for recurrent respiratory papillomatosis(RRP). Representative articles were searched, selected and reviewed. Human papilloma virus type 6 and 11 accounts for majority of cases of RRP. Hoarseness, stridor, chronic cough, dyspnoea are common presenting clinical presentation of RRP. Surgery is the treatment of choice and use of CO2 laser has been the mainstay of treatment modality. Recently photodynamic therapy, adjuvant therapy like antiviral therapy, immunotherapy and Human papilloma virus vaccines has shown efficacy in treatment of RRP.

Keywords: human papilloma virus, Recurrence, respiratory papillomatosis