A CLINICOPATHOLOGICAL STUDY OF MASSES ARISING FROM SINONASAL TRACT AND NASOPHARYNX

Abstract

Objectives:

To find the occurrence of various masses arising from the sinonasal tract and nasopharynx and to categorize them into non-specific, non-neoplastic and neoplastic and also to find the correlation between various clinical modes of presentation and histological types of these masses.

Material & Methods:

A prospective study was carried out for one year from Feburary 2010 toJanuary 2011 in a tertiary care hospital. Total of 94 masses arising from sinonasal tract and nasopharynx undergoing either incisional biopsy or surgical excision with proper history and imaging were included in this study.

Results:

The total percentage of these tumors in the one year period was 3.52%. A total of 4 non-specific lesions, 49 non-neoplastic masses, 17 benign neoplastic masses and 24 malignant neoplastic masses were found.

Conclusion:

Non-neoplastic masses were the majority in number (52.12%). Among the neoplastic masses (43.61%) malignant neoplasms constituted 25.53%, a vast majority being nasopharyngeal carcinomas. Immunohistochemistry further helped to differentiate undifferentiated carcinomas into epithelial and lymphoid malignancies.

Keywords: Clinicopathological study, Mass, nasopharynx, Sinonasal tract